<Body><script type="text/javascript"> function setAttributeOnload(object, attribute, val) { if(window.addEventListener) { window.addEventListener('load', function(){ object[attribute] = val; }, false); } else { window.attachEvent('onload', function(){ object[attribute] = val; }); } } </script> <div id="navbar-iframe-container"></div> <script type="text/javascript" src="https://apis.google.com/js/plusone.js"></script> <script type="text/javascript"> gapi.load("gapi.iframes:gapi.iframes.style.bubble", function() { if (gapi.iframes && gapi.iframes.getContext) { gapi.iframes.getContext().openChild({ url: 'https://www.blogger.com/navbar.g?targetBlogID\x3d26111381\x26blogName\x3dosmar+hate+her\x26publishMode\x3dPUBLISH_MODE_BLOGSPOT\x26navbarType\x3dBLUE\x26layoutType\x3dCLASSIC\x26searchRoot\x3dhttp://osmarlexg.blogspot.com/search\x26blogLocale\x3den_US\x26v\x3d2\x26homepageUrl\x3dhttp://osmarlexg.blogspot.com/\x26vt\x3d3555106199592248677', where: document.getElementById("navbar-iframe-container"), id: "navbar-iframe" }); } }); </script>

Friday, April 14, 2006

Asian Cricket Council

The Asian Cricket Council was formed as the Asian Cricket Conference in 1983 to promote and develop the game of cricket within Asia. Full members of the acrobat downloadConference were India, Pakistan, Sri Lanka, Bangladesh, Malaysia and Singapore. The Conference became the Asian Cricket Council in 1995, and it is currently headquartered in Kuala Lumpur, Malaysia. Membership in the ACC is divided between nine full members and 11 associate members. The full members India, Pakistan, Sri Lanka, Bangladesh, Malaysia, United Arab Emirates, Hong Kong, Singapore and Nepal and the associate members are jeredyuofAfghanistan, Bahrain, Bhutan, Brunei, Iran, Kuwait, free adobe acrobatMaldives, Oman, Qatar, Saudi Arabia and Thailand. The ACC runs a development programs that supports coaching, umpiring, and sports sigiwaldbjffmedicine programs in member countries. The ACC funds this program download adobe acrobat readerfrom television revenues acrobat readercollected during adobe acrobat reader free downloadthe officially sanctioned ACC tournaments including the Asia Cup, adobe acrobatAsian Test Championship, ACC Trophy, and Asian Cricket Junior Tournaments.

Sunjit Kumar

Sunjit Kumar is a man who free acrobat readerwas raised as a chicken free adobe acrobat readerfor over 30 years of his life. A native of Suva, Fiji, Kumar was locked in a chicken coop searlass5f0as a young boy and on the death of his father was handed over to his grandfather. He received little to no attention during this time and mimicked birds as a result. Kumar escaped hagaleahu0kzand the staff at a local hospital was unsure how to treat him and confined him for 20 years, tied to his bed for most of it. In 2004 with Kumar aged 32, Elizabeth Clayton discovered him and it acrobat distilleradobe acrobatwas found that he suffered no mental defects and his condition was due to the free acrobat readeryears and years of neglect and abuse, concluding that Kumar adapted to life as a chicken, mimicking them by perching, adobe acrobat 70picking at food, hopping about, even mannerisms and speech was all chickenlike. Since Clayton took over care of Kumar, she claims he has made much progress, now learning to walk and speak like a human.

Poste restante

Poste restante is a service provided by mails where the post office holds mail that has a notation written on it until the recipient calls for it. This is useful for travellers. In general, this notation contains the word POSTE RESTANTE, the full name of the recipient (as on the identification presented to verify the identity, download adobe acrobat readerand with the adobe acrobatsurname (if any) listed first for ease of sorting), and the name of the destination post office. As adobe acrobat readera courtesy to the postmaster, an expected date of pick-up is adobe acrobat free downloadalso indicated. adobe acrobat free downloadEach postal system has its own regulation on how acrobat readerto handle dontayerde5the service, including the length they beric2e4jhold the mail before discarding. msg:stub

1998 DK36

1998 DK36 (also written Astronomical naming conventions Minor-planets) is possibly the first Apohele asteroid (asteroid that is always closer to the Sun than Earth) detected. It was discovered by David J. Tholen, but is now considered lost and does not appear in authoritative catalogs. While its orbital elements have not been well established, its aphelion (farthest edelmarppd5acrobat reader downloaddistance from Sun) was determined faruqlg62to be less than the Earths distance to the Sun. Therefore, it has a claim to title first Apohele detected, if not first Apohele confirmed, acrobat reader downloadwhich goes adobe acrobat reader free downloadto adobe acrobat reader free download2003 acrobat reader free downloadCP20. free adobe acrobatMinorPlanets-Footer stub

Celtic music

The term Celtic music encompasses Irish traditional music and traditional musics of Scotland, Cape Breton Island and Maritime Canada, Quebec, Wales, the Isle of Man, Northumberland (northern England), Brittany (northwestern France), Cornwall, and Galicia (Spain) (northwestern Spain). The term, though widely used, is eschewed by many traditionalists. Celticmusic At issue is the lack of many common threads uniting the Celtic peoples listed above. While the ancient Celts undoubtedly had their own musical styles, these have grown and evolved to the point where considering any modern styles reminiscent of ancient Celtic music is misleading. There is also tremendous variation between Celtic regions. Ireland and Scotland, for example, have living traditions of language and music, whereas Cornwall and the Isle of Man, in contrast, have only revivalist movements that have yet to take hold. Galicia has had little or no Celtic musical influence for several centuries, but is still grouped with the others. Thus, traditionalists, and most musicology scholars dispute that the Celtic lands have any folk connections to each other. On the other hand, it is indisputable that related musical styles have been recorded and performed by and for persons living in all the Celtic lands, and thus there is such a adobe acrobat reader free downloadthing a musical tradition uniting these areas it is simply a form of popular music instead of folk music, whether or not this distinction is important is a matter of taste. Many critics of the idea of modern Celtic music claim that the idea is the creation of modern marketing acrobat reader free downloaddesigned to stimulate regional identity in the creation of a consumer niche. Common characteristic Celtic musical forms include jigs, reel (dance), hornpipe, polkas, strathspey (Scotland) and slow airs. Much of the music is typified by strong, repeating melodies in a set rhythm, which reflects a background as dance music. Ballads are also common. Largely through the adobe acrobat downloadimmigration of the download adobe acrobat readerScotch-Irish, Celtic music richd39rwas the foundation for Appalachian folk music in the United States. The Celtic music scene involves a large number of music festivals. Some of morholtpszcthe most prominent include Celtic acrobat distillerColors (Nova Scotia), Celtic Connections (Glasgow) and Festival Interceltique (Lorient, free adobe acrobatBrittany). The Breton musician Alan Stivell claimed (translation by Steve Winick) As on the linguistic plane, there are two branches, the Gaelic branch and the Brythonic branch, which differentiate themselves mostly by the extended range (sometimes more than two octaves) of Irish and Scottish melodies and the closed range of Breton and Welsh melodies (often reduced to a half-octave), and by the frequent use of the pure pentatonic scale in Gaelic music.

Long QT syndrome

The long QT syndrome (LQTS) is a heart disease in which there is an abnormally long delay between the electrical excitation (or depolarization) and relaxation (repolarization) of the ventricle (heart) of the heart. It is associated with syncope (loss of consciousness) and with sudden death due to left ventricle arrhythmias. Arrhythmias in individuals with LQTS are often associated with exercise or excitement. The cause of sudden cardiac death in individuals with LQTS is ventricular fibrillation. Individuals with LQTS have a prolongation of the QT interval on the electrocardiogram. The Q point on the electrocardiogram corresponds to the beginning of ventricular depolarization while the T point corresponds to the beginning of ventricular repolarization. The QT interval is measured from the Q point to the end of the T wave. While many individuals with LQTS have persistent prolongation of the QT interval, some individuals do not always show the QT prolongation, in these individuals, the QT interval may prolong with the administration of certain medications.


The two most common types of LQTS are genetic and drug-induced. Genetic LQTS can arise from mutation to one of several genes. These mutations tend to prolong the duration of the ventricular action potential (APD), thus lengthening the QT interval. LQTS can be inherited in an autosomal dominant or an autosomal recessive fashion. The autosomal recessive forms of LQTS tend to have a more severe phenotype, with some variants having associated syndactyly or congenital neural deafness. A number of specific genes loci have been identified that are associated with LQTS. Following is a list of the most common mutations:
LQT1 - mutations to the alpha subunit of the slow delayed rectifier potassium channel (KCNQ1 or KvLQT1). The current through the heteromeric channel (KCNQ1+KCNE1) is known as IKs This download adobe acrobat readermutation is thought to cause LQT by reducing the amount of repolarizing action potential current that prolongs action potential duration (APD). These mutations tend to be the most common yet least severe.
LQT2 - mutations to the alpha subunit of the fast delayed rectifier potassium channel (HERG). Current through this channel is known as IKr This phenotype is also probably caused by a reduction in repolarizing current.
LQT3 - mutations to the alpha subunit of the sodium channel (SCN5A). Current through is channel is commonly referred to as INa Depolarizing current through the channel late in the action potential is thought to prolong APD. The late current is due to failure of the channel to remain inactivated and hence enter a bursting mode in which significant current can enter when it should not. These mutations are more lethal but less common.
LQT4 - mutations in an anchor protein Ankyrin B which anchors the ion channels in the cell. Very rare.
LQT5 - mutations in the beta subunit MinK which coassembles with KvLQT1.
LQT6 - mutations in the beta subunit MiRP1 which coassembles with HERG.
LQT7 - mutations in the potassium channel KCNJ2 which leads to Andersen-Tawil syndrome.
LQT8 - mutations in the calcium channel CACNA1c which leads to Timothys syndrome Other mutations affect the beta subunits ion channels or even ryanodine receptors. For example LQT6 affects minK (aka KCNE1) which is the beta subunit that coassembles with KCNQ1 to form IKs channels. Drug induced LQT is usually a result of treatment by Cardiac arrhythmias drugs such as amiodarone or a number of other drugs that have been reported to cause this problem (e.g. cisapride). Genetic mutations may make one more prone to drug induced LQT.


LQT1 is the most common type of long QT syndrome, making up about 40 to 55 percent of all cases. The LQT1 gene is named KVLQT1 (also known as KCNQ1), and has been isolated to chromosome 11p15.5. Studies of the gene product suggest that KVLQT1 encodes for a voltage-gated potassium channel that is highly expressed in the heart. It is believed that the product of the KVLQT1 gene produces an alpha subunit that interacts with other proteins (particularly the minK beta subunit) to create the IKs ion channel, which is responsible for the delayed potassium rectifier current of the cardiac action potential. The KVLQT1 gene can be inherited in an autosomal dominant or an autosomal recessive pattern in the same family. In the autosomal recessive mutation of this gene, homozygous mutations of KVLQT1 leads to severe prolongation of the QT interval (due to near-complete loss of the IKs ion channel), and is associated with increased risk of ventricular arrhythmias and free adobe acrobatcongenital deafness. Most individuals with LQT1 show paradoxical prolongation of the QT interval with infusion of epinephrine. This can also unmark latent carriers of the LQT1 gene. Many missense mutations of the LQT1 gene have been identified. These are often associated with a high risk percentage of symptomatic carriers and sudden death.


The LQT2 type is the second most common gene location that is affected in long QT syndrome, making up about 35 to 45 percent of all cases. This form of long QT syndrome most likely involves mutations of the human ether-a-go-go related gene (HERG) on chromosome 7. The HERG gene (also known as KCNH2) is part of the rapid component of the potassium rectifying current (IKr. (The IKr current is mainly responsible adobe acrobat reader free downloadfor the termination of the cardiac action potential, and therefore the length of the QT interval.) The normally functioning HERG gene allows protection against early after depolarizations (EADs). Most drugs that cause long QT syndrome do so by blocking the IKr current via the HERG gene. These include erythromycin, terfenadine, and ketoconazole.


The LQT3 type of long QT syndrome involves mutation of the gene that encodes the alpha subunit of the sodium ion channel. This gene is located on chromosome 3p21-24, and is known as SCN5A (also hH1 and NaV1.5). The mutations involved in LQT3 slow the inactivation of the Na channel, resulting in prolongation of adobe acrobat readerthe Na influx during depolarization. Paradoxically, the mutant sodium channels inactivate acrobat downloadmore quickly, and may open repetitively during the action potential. A large number of mutations have been characterized as leading to or predisposing LQT3. Calcium has been suggested as a regulator of SCN5A, and the effects of calcium on SCN5A may begin to explain the mechanism by which some these mutations cause LQT3.

Associated syndromes

A number of syndromes are associated with LQTS.

Andersen-Tawil syndrome

Andersen-Tawil syndrome is an autosomal dominant form of LQTS associated with skeletal deformities.

Jervell derebourne3xstand Lange-Nielsen syndrome

The Jervell and Lange-Nielsen syndrome (JLNS) is an autosomal recessive form of LQTS with associated congenital deafness. It is caused specifically by mutation of the KCNE1 and KCNQ1 genes. In untreated individuals with JLNS, about 50 percent die by the age of 15 years due to ventricular arrhythmias.

Romano-Ward syndrome

Romano-Ward syndrome is an autosomal dominant form of LQTS that is not associated with deafness.

Mechanism of arrhythmia generation

All forms of the long QT syndrome involve an abnormal repolarization of the heart. The abnormal repolarization causes differences in the refractoriness of the myocytes. After-depolarizations (which occur more commonly in LQTS) can be propogated to neighboring cells due to the differences in the refractory periods, leading to re-entrant ventricular arrhythmias. It is believed that the after-depolarizations that are seen in LQTS are due to re-opening of L-type sodium channels during the plateau phase of the cardiac action potential. Since adrenergic stimulation can increase the activity of these channels, this is an explanation for why the risk of sudden death larenzo52ddin individuals with LQTS is increased during increased adrenergic states (ie: exercise, excitement).

Treatment options

There are two treatment options in individuals with LQTS: arrhythmia prevention, and arrhythmia termination. Arrhythmia suppression involves the use of medications or surgical procedures that attack the underlying cause of the arrhythmias associated with LQTS. Since the cause of arrhythmias in LQTS is after depolarizations, and these after depolarizations are increased in states of adrenergic stimulation, steps can be taken to blunt adrenergic stimulation in these individuals. acrobat reader downloadThese include administration of beta blocker and amputation of the cervical sympathetic chain. Arrhythmia termination involves stopping a life-threatening arrhythmia once it has already occurred. The only effective form of arrhythmia termination in individuals with LQTS is placement of an implantable cardioverter-defibrillator (ICD). With better knowledge of the genetics underlying the long QT syndrome, more precise treatments will be readily available.1


1. Compton SJ, Lux RL, Ramsey MR, Strelich KR, Sanguinetti MC, Green LS, Keating MT, Mason JW. Genetically defined therapy of inherited long-QT syndrome. Correction of abnormal repolarization by potassium. Circulation. 1996 Sep 1,94(5):1018-22. (Retrieve&db pubmed&dopt Abstract&list-uids 8790040 Medline abstract)

Henri Marteau

Henri Marteau (March 31, 1874 - 1934) was a French violinist and composer. He was born in Reims, France. His father was a well known amateur violinist of that city, and took a great interest in musical affairs. His mother was an excellent pianist, who had studied under Mme. Schumann. Through the influence of Sivori, Marteaus parents were easily persuaded to allow their son to adopt a musical career, and he showed remarkable aptitude in his studies, first under Bunzl, and later under Leonard. His professional debut was made when only ten years old, at a concert given by the Vienna Philharmonic Society, conducted by Richter. A tour through Switzerland and Germany followed. A year later Charles Gounod selected this young violinist to play the obbligato of a piece composed for the Joan of Arc Centenary Celebration at Reims. Marteau made his debut in acrobat readerLondon in 1888, at a Richter concert. In 1892 he gained the first place prize at adobe acrobatthe Paris Conservatory, and Jules Massenet wrote a violin concerto especially for his benefit. A further series of tours followed. Twice he visited darelene1lusadobe acrobat free downloadAmerica, once in 1893, and once in 1898, and he visited Russia 1897-1899. He was then engaged in teaching, and for a time was professor of the violin at Geneva Conservatoire. On the download adobe acrobat readerdeath of Joachim, Marteau was called to the Hochsschule of Berlin, where adobe acrobat readerhe became rosemundan9w9head of the violin deparment. His was the composer of a cantata for adobe acrobatsoprano, chorus and orchestra, entitled La voix de Jeanne dArc. He died in Lichtenberg, Sweden.